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祝贺周云兵和刘妙昌老师指导研究生安翠在Organic Letters发表学术论文

发布时间:2019-09-10    来源:BETVlCTOR手机登录    作者:    点击次    [点击关闭]

标题(中文):硒自由基介导的联环化:硒化苯并呋喃(苯并噻吩)的合成

标题(英文):Selenium Radical Mediated Cascade Cyclization: Concise Synthesis of Selenated Benzofurans (Benzothiophenes)

刊物名称及期号、页码: Organic Letters, 2019, 21, 6710-6714

作者姓名(中文):安翠,郦晨园,黄小波,高文霞,周兵,刘妙昌,吴华

作者姓名(英文)Cui An, Chen-Yuan Li, Xiao-Bo Huang, Wen-Xia Gao, Yun-Bing Zhou*, Miao-Chang Liu*, Hua-Yue Wu.

摘要(英文):Presented in this work is a novel methodology for the synthesis of selenated benzofurans (or benzothiophenes) via AgNO2-catalyzed radical cyclization of 2-alkynylanisoles (or 2-alkynylthioanisoles), Se powder, and arylboronic acids. This method enables the construction of a benzofuran (benzothiophene) ring, two C–Se bonds, and a C–O(S) bond as well as the cleavage of a C–O(S) bond in a single step. Preliminary mechanistic studies imply that the AgNO2-catalyzed cyclization proceeds via an aryl selenium radical intermediate.

原文链接: https://doi.org/10.1021/acs.orglett.9b02315