标题:Copper-catalyzed C–O bond cleavage and cyclization: synthesis of indazolo[3,2-b]quinazolinones
Abstact:The first example of a copper-catalyzed halogen-free protocol to construct indazolo[3,2-b]quinazolinones was developed through sequential inert C–O bond cleavage followed by intramolecular C–N bond formation. This protocol represents an efficient synthetic tool for accessing a more diverse range of functionalized indazolo[3,2-b]quinazolinones. The structure of the newly synthesized indazolo[3,2-b]quinazolinones was unambiguously confirmed by X-ray crystal diffraction analysis.
链接:http://pubs.rsc.org/is/content/articlehtml/2017/ob/c6ob02352e
C6OB02352E