姓名: Ebrahim-Alkhalil M. A. Ahmed (伊布拉辛) 学位：博士Ph.D.  毕业学校：中国科学技术大学

University of Science and Technology of China (USTC) 籍贯：苏丹 Sudan

职称/职务：讲师/硕导 专业：有机化学 系：化学系 科研团队：BETVlCTOR手机登录碳能源与催化科学研究所

电子邮箱：khalil52@wzu.edu.cn; khalil52@ustc.edu.cn ORCID: 主要从事于有机合成、不对称合成、均相催化、过渡金属催化的交叉偶联反应开环反应等合成方 CC/CX CC/CX Organic synthesis, asymmetric synthesis, homogeneous catalysis, transition-metal-catalyzed cross- couplingreactions,ring-openingreactionstoinnovateanddesigndevelopedsyntheticmethodstoward synthesis C−C/ C−X bond-forming compounds via C−C/ C−X bond activation and cleavage, Analytical techniques for characterization and analysis molecules and complexes. He has engaged in a number of related research work including transition-metal-catalyzed ring-coupling reactions of three-membered ring heterocycles; For instance, copper-catalyzed ring-opening reactions of epoxides/N-sulfonyl aziridines with gem-diborylmethane and diboron reagents. Palladium-catalyzed regioselective activation of gem- difluorinated cyclopropanes, to construct 2-fluoroallylic amines, ethers, esters, alkylation, arylation, alkynylation products. Up to now, he has published in the first level of SCI 7 papers (total of IF = 50.486) as first author in Angewandte Chemie International Edition, Organic Letters, Chemical Communications. He participated in writing Book Chapter in Science of Synthesis, Advances in Organoboron Chemistry towards Organic Synthesis. He attained 2017 Youth Innovation Fund Program of USTC at University of Science and Technology of China, from 2018/01 to 2019/12 as well as President’s International Fellowship Initiative Program (PIFI) at University of Science and Technology of China (USTC), from 2018/01 to 2019/12.

【工作/教育经历, Work/ Education Experience】

2020.7 −至今，讲师/硕士生导师，BETVlCTOR手机登录 (Wenzhou University; WZU), BETVlCTOR手机登录(College of Chemical and Materials Engineering), 材料科学与工程系(Department of Materials Science and Engineering).

2017.7 − 2020.6，博士后(有机化学) Postdoc Fellow (Organic Chemistry), 中国科学技术大学(University of Science and Technology of China; USTC), 化学与材料科学学院 (School of Chemistry & Materials Science), 导师：（合作导师：龚流柱教授、傅尧教授）。

Research Focus: Develop new synthetic approach cross-coupling reactions catalysis of gem-Difluorinated Cyclopropanes toward synthesis C–C bond-formation {C(sp³)–C(sp)/C–(sp²)/C(sp³)} as well as regio- and enantioselective studies.

2013.9 − 2017.6，博士(有机化学) Doctor of Philosophy (Ph.D.), Organic Chemistry, 中国科学技术大学中国科学技术大学(University of Science and Technology of China (USTC), 化学与材料科学学院(School of Chemistry & Materials Science), 导师：傅尧教授。

Thesis title: Transition-Metal-Catalyzed Cross-Coupling Reactions of Epoxides and gem-Difluorinated Cyclopropanes.

Research Focus: Catalytic strategies of copper catalyst in organic synthesis of β- and γ-hydroxyl boronic esters from epoxides and their applications derived possibilities in further organic reactions. Additionally, palladium catalyst to synthesize 2-fluorinated allylic scaffolds via C–C bond activation/C–F bond cleavage.

2009.9 − 2013.7 ，硕士（有机化学) Master of Science (M.Sc.), Organic Chemistry, 西北师范大学(Northwest Normal University; NWNU), 化学与化工学院 (College of Chemistry and Chemical Engineering), 导师：胡玉来教授。

Thesis title: Highly Enantio- and Diastereoselective Mannich Reaction of β-Ketoesters with Fluorinated Aldimine Catalyzed by Bifunctional Thiourea & Process for Preparing 1-(2’-HaloPhenyl)-3-Methyl Butanone-1.

Research Focus: Asymmetric organic synthesis for preparing organofluorine compounds using bifunctional thiourea catalysts. Organic synthesis of ketone intermediate for preparation Repaglinide drug (non-sullfonylurea hypoglycemic agent).

2000.8 − 2005.10，本科(化学专业) Bachelor of Science (B.Sc.), Honor’s degree of Chemistry, 喀土穆大学（University of Khartoum; UofK), 科学院 (Faculty of Science), 科学系(Department of Chemistry).

【教学, Teaching】

§ Full-time Teaching Assistant (TA) at 喀土穆大学（University of Khartoum), 科学院 (Faculty of Science), 科学系 (Department of Chemistry), 喀土穆, 苏丹 Khartoum-Sudan, since 2006 until 2009. Lesson subjects (Inorganic Chemistry, Analytical Chemistry, Organic and Physical Chemistry)

§ Lecturer position at 喀土穆大学（University of Khartoum), 科学院 (Faculty of Science), 科学系

(Department of Chemistry), 喀土穆, 苏丹 Khartoum-Sudan, since 2013 until 2017.

【员工培养, Student Supervision】

§ Zhang Jun, 硕士员工M.Sc. student, BETVlCTOR手机登录 Wenzhou University, Spring 2021−Present.

§ Yu Guo, 硕士员工 M.Sc. student, BETVlCTOR手机登录 Wenzhou University, Summer 2020−Present.

§ Ayman M. Y. Suliman, 博士员工Ph.D. student, University of Science and Technology of China (USTC), 2018−Present.

§ Kai-Feng Zhu, 硕士员工M.Sc. student, University of Science and Technology of China, 2019−2020.

§ Shang-Hai Yu, 硕士员工 M.Sc. student, University of Science and Technology of China, Spring and Summer 2016.

§ Chu-Guo Yu, 硕士员工 M.Sc. student, University of Science and Technology of China, Spring and Summer 2014−2015.

【科研成果, Scientific Achievements】

#共同一作 Co-first author。

【书/书章节，Book Chapter】

(1) Tian-Jun Gong^#, Ebrahim-Alkhalil M. A. Ahmed^#, and Yao Fu*. As Chapter 14 in the book of Science of Synthesis, "Advances in Organoboron Chemistry towards Organic Synthesis", Fernández, E., Ed.; Thieme: Stuttgart, 2019; p 459−500.

Book link: https://www.thieme.com/books-main/chemistry/product/5679-science-of- synthesis- advances-in-organoboron-chemistry-towards-organic-synthesis

【一作/通讯作者 SCI 论文,First-author and Co-first author Journal Papers】

(1) Jun Xu^{#, Ebrahim-Alkhalil M. A. Ahmed#, Bin Xiao, Qian-Qian Lu, Yun-Long Wang, Chu-Guo Yu, and Yao Fu*. "Palladium-Catalyzed Regioselective Activation of gem-Difluorinated Cyclopropanes: A Highly Efficient Approach to 2-Fluorinated Allylic Scaffolds". Angew. Chem. Int. Ed., 2015, 54, 8231–8235. (IF: 12.257, SCI 一区).}

Paper link: https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201502308

(2) Ebrahim-Alkhalil M. A. Ahmed, Zhen-Qi Zhang, Tian-Jun Gong, Wei Su, Xiao-Yu Lu, Bin Xiao* and Yao Fu*. "Copper-Catalyzed Cross-Coupling Reactions of Epoxides with gem-Diborylmethane: Access to γ- Hydroxyl Boronic Esters". Chem. Commun., 2016, 52, 4891–4893. (IF: 6.164, SCI 一 区 ). This study was highlighted in X-mol magazine (http://www.x-mol.com/news/2498).

Paper link: https://pubs.rsc.org/en/content/articlelanding/2016/CC/C5CC09817C#!divAbstract

(3) Ebrahim-Alkhalil M. A. Ahmed, Xi Lu, Tian-Jun Gong, Zhen-Qi Zhang, Bin Xiao* and Yao Fu*. "Copper- Catalyzed/Mediated Borylation Reactions of Epoxides with Diboron Reagents. Access to β-Hydroxyl Boronic Esters". Chem. Commun., 2017, 53, 909–912. (IF: 6.164, SCI 一区).

Paper link: https://pubs.rsc.org/en/content/articlelanding/2017/CC/C6CC07924E#!divAbstract

(4) Ebrahim-Alkhalil M. A. Ahmed, Ayman M. Y. Suliman, Tian-Jun Gong* and Yao Fu*. Palladium-Catalyzed Stereoselective Defluorination Arylation/ Alkenylation/Alkylation of gem-Difluorinated Cyclopropanes". Org. Lett., 2019, 21, 5645−5649. (IF: 6.579, SCI 一区).

Paper link: https://pubs.acs.org/doi/10.1021/acs.orglett.9b01979

(5) Ebrahim-Alkhalil M. A. Ahmed, Ayman M. Y. Suliman, Tian-Jun Gong* and Yao Fu*. "Access to Divergent Fluorinated Enynes and Arenes via Palladium-Catalyzed Ring-Opening Alkynylation of gem-Difluorinated Cyclopro-panes". Org. Lett., 2020, 22, 1414−1419. (IF: 6.579, SCI 一区).

Paper link: https://pubs.acs.org/doi/10.1021/acs.orglett.0c00022

(6) Ayman M. Y. Suliman^{#, Ebrahim-Alkhalil M. A. Ahmed#, Tian-Jun Gong* and Yao Fu*. "Cu/Pd-Catalyzed cis-Borylfluoroallylation of Alkynes for the Synthesis of Boryl-Substituted Monofluoroalkenes". Org. Lett. 2021, 23, 3259−3263. (IF: 6.579, SCI 一区).}

Paper link: https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.1c00668

(7) Ayman M. Y. Suliman^{#, Ebrahim-Alkhalil M. A. Ahmed#, Tian-Jun Gong* and Yao Fu*. "Three- Component Reaction of gem-Difluorinated Cyclopropane with Alkenes and B2pin2 for the Synthesis of Monofluoroalkenes". Chem. Commun. 2021, doi.org/10.1039/D1CC01620B. (IF: 6.164, SCI 一区).}

Paper link: https://pubs.rsc.org/en/content/articlepdf/2021/cc/d1cc01620b?page=search

(8) Lingchen He, Ebrahim-Alkhalil M. A. Ahmed, Hongxin Liu, Xingen Hu*, Hong-ping Xiao, Juan Li, and Jun Jiang*. "Asymmetric Construction of α‑Substituted β‑Hydroxy Lactones via Ni Catalyzed Decarboxylative Addition Reaction". J. Org. Chem., 2021, 86, 4825−4834. (IF: 4.335, SCI 二区).

Paper link: https://pubs.acs.org/doi/10.1021/acs.joc.0c02854

【专利，Patents】

(1) Yu-lai Hu, Ebrahim-Alkhalil M. A. Ahmed, Ke-hu Wang, Dan-feng Huang. "Process for Preparing 1-(2’- Halophenyl)-3-Methyl Butanone-1". Chinese Pat. Appl. CN 102942464 A, 27 Feb. 2013.

【Conference Paper, 会议论文】

(1) Ebrahim-Alkhalil M. A. Ahmed, Ying-peng Su, Ke-hu Wang, Dan-feng Huang, Yu-lai Hu*. "Highly Enantio- and Diastereoslective Mannich Reaction of β-Ketoesters with Fluorinated Aldimine Catalyzed by Bifunctional Thiourea". 28^th annual meeting of chemical society of Gansu (http://hxhg.ldxy.edu.cn/info/news/nianhui/nr/113988.htm), July 2013.

【科研项目及经费, Awards of Research Founding】

§ 中国科学技术大学，中国科学技术大学青年创新基金项目, Research Fund of Postdoc, 2017 Youth Innovation Fund Program of USTC at University of Science and Technology of China; on Palladium-Catalyzed Cross-Coupling of gem-Difluorinated Cyclopropanes with Organoboron Reagents . Awarded 150,000 RMB (主持)，经费：15 万，期限：2018.1 − 2019.12。

§ 中国科学院，国际人才计划博士后项目, 2018 President’s International Fellowship Initiative

Program (PIFI) at University of Science and Technology of China; on Transition-Metal-Catalyzed Cross-Coupling of gem-Difluorinated Cyclopropanes and Alkenes with Organoboron Reagents. Awarded 500,000 RMB (主持)，经费：50 万，期限：2018.1 − 2019.12。

【荣誉和奖励，Awards and Fellowships】

§ Chinese Academic of Science & the World Academic of Science CAS-TWAS Fellowship at University of Science and Technology of China), 2013.

§ The excellent Ph.D. student for the best academic performance under "CAS-TWAS" Fellowship Program for Ph.D. international students at University of Science and Technology of China, 2017.

§ Faculty Prize for third year (B.Sc., Chemistry) for best academic performance at Faculty of Science, University of Khartoum, 2003.